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6D9R

The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BHypoxanthine phosphoribosyltransferasepolymer18320503.62UniProt (A0A1S0QLD4)
Pfam (PF00156)
UniProt (by SIFTS) (B9ZW32)
In PDB
Bacillus anthracisHPRT
2A, B9-DEAZAGUANINEnon-polymer150.12Chemie (9DG)
3A, B1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranosenon-polymer390.12Chemie (PRP)
4A, BMAGNESIUM IONnon-polymer24.34Chemie (MG)
5A, BDI(HYDROXYETHYL)ETHERnon-polymer106.15Chemie (PEG)
6A, BACETATE IONnon-polymer59.03Chemie (ACT)
7B, A1,2-ETHANEDIOLnon-polymer62.111Chemie (EDO)
8waterwater18.0317Chemie (HOH)
Sequence modifications
A, B: 1 - 180 (UniProt: A0A1S0QLD4)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight41007.3
Non-Polymers*Number of molecules27
Total formula weight2568.1
All*Total formula weight43575.4
*Water molecules are not included.

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PDB entries from 2024-10-16

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