6D9R
The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hypoxanthine phosphoribosyltransferase | polymer | 183 | 20503.6 | 2 | UniProt (A0A1S0QLD4) Pfam (PF00156) UniProt (by SIFTS) (B9ZW32) | Bacillus anthracis | HPRT |
| 2 | C, O (A, B) | 9-DEAZAGUANINE | non-polymer | 150.1 | 2 | Chemie (9DG) | |||
| 3 | D, P (A, B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) | |||
| 4 | E, F, Q, R (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | G, H, S, T, U (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | I, V, W (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | AA, BA, CA, J, K... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 11 | Chemie (EDO) | |||
| 8 | DA, EA (A, B) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 180 (UniProt: A0A1S0QLD4)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41007.3 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2568.1 | |
| All* | Total formula weight | 43575.4 |
