6D7Q
Crystal Structure of Rat TRPV6*-Y466A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Transient receptor potential cation channel subfamily V member 6 | polymer | 672 | 77041.4 | 1 | UniProt (Q9R186) Pfam (PF12796) Pfam (PF00520) In PDB | Rattus norvegicus (Rat) | TrpV6,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2 |
| 2 | A | 2-aminoethyl diphenylborinate | non-polymer | 225.1 | 1 | Chemie (FZ4) | |||
| 3 | A | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID | non-polymer | 214.3 | 1 | Chemie (DTB) | |||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: 1 - 669 (UniProt: Q9R186)
| PDB | External Database | Details |
|---|---|---|
| Tyr 62 | Ile 102 | conflict |
| Asn 92 | Leu 132 | conflict |
| Gln 96 | Met 136 | conflict |
| Ala 466 | Tyr 506 | engineered mutation |
| Val 670 | - | expression tag |
| Pro 671 | - | expression tag |
| Arg 672 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 77041.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 479.4 | |
| All* | Total formula weight | 77520.8 |
