6D4F
Crystal structure of PTP epsilon D2 domain (A455N/V457Y/E597D)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Receptor-type tyrosine-protein phosphatase epsilon | polymer | 279 | 32426.8 | 1 | UniProt (P23469) Pfam (PF00102) In PDB | Homo sapiens (Human) | R-PTP-epsilon |
| 2 | A | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 3 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 425 - 700 (UniProt: P23469)
| PDB | External Database | Details |
|---|---|---|
| Gly 422 | - | expression tag |
| Gly 423 | - | expression tag |
| Gly 424 | - | expression tag |
| Asn 455 | Ala 455 | engineered mutation |
| Tyr 457 | Val 457 | engineered mutation |
| Asp 597 | Glu 597 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32426.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 238.3 | |
| All* | Total formula weight | 32665.1 |
