6D2L

Crystal structure of human CARM1 with (S)-SKI-72

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Histone-arginine methyltransferase CARM1	polymer	344	38976.5	6	UniProt (Q86X55) Pfam (PF06325) Pfam (PF22528)	Homo sapiens (Human)	Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4
2	G, L, M, P, Q... (A, B, C, D, E...)	(2S,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-hydroxyphenyl)ethyl]hexanamide	non-polymer		604.7	6	Chemie (FTG)
3	H, N, S (A, C, F)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	I, J (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	K, O, T (A, C, F)	UNKNOWN ATOM OR ION	non-polymer			3	Chemie (UNX)
6	U, V, W, X, Y... (A, B, C, D, E...)	water	water		18.0	761	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	233858.7
Non-Polymers*	Number of molecules	14
	Total formula weight	4100.6
All*	Total formula weight	237959.3

*Water molecules are not included.