6D12
Crystal structure of C-terminal xRRM domain of human Larp7 bound to 7SK stem-loop 4 RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | La-related protein 7 | polymer | 113 | 13006.6 | 2 | UniProt (Q4G0J3) Pfam (PF08777) | Homo sapiens (Human) | La ribonucleoprotein domain family member 7,P-TEFb-interaction protein for 7SK stability,PIP7S |
| 2 | C (C) | human 7SK RNA stem-loop 4 | polymer | 38 | 12296.3 | 1 | Homo sapiens | ||
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 445 - 556 (UniProt: Q4G0J3)
| PDB | External Database | Details |
|---|---|---|
| Ser 444 | - | expression tag |
| Mse 475 | Leu 475 | engineered mutation |
| Leu 501 | Glu 501 | engineered mutation |
| Leu 504 | Gln 504 | engineered mutation |
| Mse 521 | Leu 521 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38309.6 | |
| All* | Total formula weight | 38309.6 |
