6CYV
E. coli DHFR ternary complex with NADP and dihydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 165 | 18848.2 | 1 | UniProt (P0ABQ5) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | DIHYDROFOLIC ACID | non-polymer | 443.4 | 1 | Chemie (DHF) | |||
| 4 | D (A) | water | water | 18.0 | 241 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ5)
| PDB | External Database | Details |
|---|---|---|
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18848.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1186.8 | |
| All* | Total formula weight | 20035.0 |
