6CXC
3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (X, G, I) | R4.C6 Fab Heavy Chain | polymer | 118 | 12831.4 | 3 | Mus musculus (Mouse) | ||
| 2 | B, D, F (Y, J, K) | R4.C6 Fab Light Chain | polymer | 122 | 13457.2 | 3 | Mus musculus (Mouse) | ||
| 3 | G, H, I, J, K... (A, B, C, D, E...) | Fusion glycoprotein F0, Envelope glycoprotein chimera | polymer | 548 | 60728.0 | 6 | UniProt (P03420) UniProt (M1E1E4) | Human respiratory syncytial virus A (strain A2) | Protein F |
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
A, B, C, D, E, F: 26 - 526 (UniProt: P03420)
A, B, C, D, E, F: 538 - 567 (UniProt: M1E1E4)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Pro 102 | conflict |
| Gln 133 | Arg 133 | conflict |
| Gln 135 | Arg 135 | conflict |
| Gln 136 | Arg 136 | conflict |
| Val 379 | Ile 379 | conflict |
| Val 447 | Met 447 | conflict |
| Gly 527 | - | linker |
| Ala 528 | - | linker |
| Leu 529 | - | linker |
| Val 530 | - | linker |
| Pro 531 | - | linker |
| Arg 532 | - | linker |
| Gly 533 | - | linker |
| Ser 534 | - | linker |
| Pro 535 | - | linker |
| Gly 536 | - | linker |
| Ser 537 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
| His 571 | - | expression tag |
| His 572 | - | expression tag |
| His 573 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 443233.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 444561.1 |
