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6CXC

3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein

Functional Information from GO Data
ChainGOidnamespacecontents
A0005886cellular_componentplasma membrane
A0016020cellular_componentmembrane
A0019031cellular_componentviral envelope
A0019064biological_processfusion of virus membrane with host plasma membrane
A0020002cellular_componenthost cell plasma membrane
A0042802molecular_functionidentical protein binding
A0044177cellular_componenthost cell Golgi apparatus
A0044178cellular_componenthost cell Golgi membrane
A0046718biological_processsymbiont entry into host cell
A0055036cellular_componentvirion membrane
A0060141biological_processpositive regulation of syncytium formation by virus
A0098670biological_processentry receptor-mediated virion attachment to host cell
B0005886cellular_componentplasma membrane
B0016020cellular_componentmembrane
B0019031cellular_componentviral envelope
B0019064biological_processfusion of virus membrane with host plasma membrane
B0020002cellular_componenthost cell plasma membrane
B0042802molecular_functionidentical protein binding
B0044177cellular_componenthost cell Golgi apparatus
B0044178cellular_componenthost cell Golgi membrane
B0046718biological_processsymbiont entry into host cell
B0055036cellular_componentvirion membrane
B0060141biological_processpositive regulation of syncytium formation by virus
B0098670biological_processentry receptor-mediated virion attachment to host cell
C0005886cellular_componentplasma membrane
C0016020cellular_componentmembrane
C0019031cellular_componentviral envelope
C0019064biological_processfusion of virus membrane with host plasma membrane
C0020002cellular_componenthost cell plasma membrane
C0042802molecular_functionidentical protein binding
C0044177cellular_componenthost cell Golgi apparatus
C0044178cellular_componenthost cell Golgi membrane
C0046718biological_processsymbiont entry into host cell
C0055036cellular_componentvirion membrane
C0060141biological_processpositive regulation of syncytium formation by virus
C0098670biological_processentry receptor-mediated virion attachment to host cell
D0005886cellular_componentplasma membrane
D0016020cellular_componentmembrane
D0019031cellular_componentviral envelope
D0019064biological_processfusion of virus membrane with host plasma membrane
D0020002cellular_componenthost cell plasma membrane
D0042802molecular_functionidentical protein binding
D0044177cellular_componenthost cell Golgi apparatus
D0044178cellular_componenthost cell Golgi membrane
D0046718biological_processsymbiont entry into host cell
D0055036cellular_componentvirion membrane
D0060141biological_processpositive regulation of syncytium formation by virus
D0098670biological_processentry receptor-mediated virion attachment to host cell
E0005886cellular_componentplasma membrane
E0016020cellular_componentmembrane
E0019031cellular_componentviral envelope
E0019064biological_processfusion of virus membrane with host plasma membrane
E0020002cellular_componenthost cell plasma membrane
E0042802molecular_functionidentical protein binding
E0044177cellular_componenthost cell Golgi apparatus
E0044178cellular_componenthost cell Golgi membrane
E0046718biological_processsymbiont entry into host cell
E0055036cellular_componentvirion membrane
E0060141biological_processpositive regulation of syncytium formation by virus
E0098670biological_processentry receptor-mediated virion attachment to host cell
F0005886cellular_componentplasma membrane
F0016020cellular_componentmembrane
F0019031cellular_componentviral envelope
F0019064biological_processfusion of virus membrane with host plasma membrane
F0020002cellular_componenthost cell plasma membrane
F0042802molecular_functionidentical protein binding
F0044177cellular_componenthost cell Golgi apparatus
F0044178cellular_componenthost cell Golgi membrane
F0046718biological_processsymbiont entry into host cell
F0055036cellular_componentvirion membrane
F0060141biological_processpositive regulation of syncytium formation by virus
F0098670biological_processentry receptor-mediated virion attachment to host cell
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2988
DetailsTOPO_DOM: Extracellular => ECO:0000269|PubMed:16160180
ChainResidueDetails
AGLN26-ASN524
BGLN26-ASN524
CGLN26-ASN524
DGLN26-ASN524
EGLN26-ASN524
FGLN26-ASN524

site_idSWS_FT_FI2
Number of Residues6
DetailsSITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11493675, ECO:0000269|PubMed:12127793
ChainResidueDetails
AARG109
BARG109
CARG109
DARG109
EARG109
FARG109

site_idSWS_FT_FI3
Number of Residues6
DetailsSITE: Cleavage; by host furin-like protease => ECO:0000269|PubMed:11369882, ECO:0000269|PubMed:12127793
ChainResidueDetails
AGLN136
BGLN136
CGLN136
DGLN136
EGLN136
FGLN136

site_idSWS_FT_FI4
Number of Residues6
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636
ChainResidueDetails
AASN27
BASN27
CASN27
DASN27
EASN27
FASN27

site_idSWS_FT_FI5
Number of Residues6
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033
ChainResidueDetails
AASN70
BASN70
CASN70
DASN70
EASN70
FASN70

site_idSWS_FT_FI6
Number of Residues18
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255
ChainResidueDetails
AASN116
DASN116
DASN120
DASN126
EASN116
EASN120
EASN126
FASN116
FASN120
FASN126
AASN120
AASN126
BASN116
BASN120
BASN126
CASN116
CASN120
CASN126

site_idSWS_FT_FI7
Number of Residues6
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220
ChainResidueDetails
AASN500
BASN500
CASN500
DASN500
EASN500
FASN500

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PDB entries from 2024-07-17

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