Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6CXC

3.9A Cryo-EM structure of murine antibody bound at a novel epitope of respiratory syncytial virus fusion protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0016020	cellular_component	membrane
A	0019031	cellular_component	viral envelope
A	0019062	biological_process	virion attachment to host cell
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0020002	cellular_component	host cell plasma membrane
A	0033644	cellular_component	host cell membrane
A	0039663	biological_process	membrane fusion involved in viral entry into host cell
A	0042802	molecular_function	identical protein binding
A	0044177	cellular_component	host cell Golgi apparatus
A	0044178	cellular_component	host cell Golgi membrane
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0055036	cellular_component	virion membrane
A	0060141	biological_process	symbiont-mediated induction of syncytium formation
A	0098670	biological_process	entry receptor-mediated virion attachment to host cell
B	0005886	cellular_component	plasma membrane
B	0016020	cellular_component	membrane
B	0019031	cellular_component	viral envelope
B	0019062	biological_process	virion attachment to host cell
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0020002	cellular_component	host cell plasma membrane
B	0033644	cellular_component	host cell membrane
B	0039663	biological_process	membrane fusion involved in viral entry into host cell
B	0042802	molecular_function	identical protein binding
B	0044177	cellular_component	host cell Golgi apparatus
B	0044178	cellular_component	host cell Golgi membrane
B	0044423	cellular_component	virion component
B	0046718	biological_process	symbiont entry into host cell
B	0055036	cellular_component	virion membrane
B	0060141	biological_process	symbiont-mediated induction of syncytium formation
B	0098670	biological_process	entry receptor-mediated virion attachment to host cell
C	0005886	cellular_component	plasma membrane
C	0016020	cellular_component	membrane
C	0019031	cellular_component	viral envelope
C	0019062	biological_process	virion attachment to host cell
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0020002	cellular_component	host cell plasma membrane
C	0033644	cellular_component	host cell membrane
C	0039663	biological_process	membrane fusion involved in viral entry into host cell
C	0042802	molecular_function	identical protein binding
C	0044177	cellular_component	host cell Golgi apparatus
C	0044178	cellular_component	host cell Golgi membrane
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0055036	cellular_component	virion membrane
C	0060141	biological_process	symbiont-mediated induction of syncytium formation
C	0098670	biological_process	entry receptor-mediated virion attachment to host cell
D	0005886	cellular_component	plasma membrane
D	0016020	cellular_component	membrane
D	0019031	cellular_component	viral envelope
D	0019062	biological_process	virion attachment to host cell
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0020002	cellular_component	host cell plasma membrane
D	0033644	cellular_component	host cell membrane
D	0039663	biological_process	membrane fusion involved in viral entry into host cell
D	0042802	molecular_function	identical protein binding
D	0044177	cellular_component	host cell Golgi apparatus
D	0044178	cellular_component	host cell Golgi membrane
D	0044423	cellular_component	virion component
D	0046718	biological_process	symbiont entry into host cell
D	0055036	cellular_component	virion membrane
D	0060141	biological_process	symbiont-mediated induction of syncytium formation
D	0098670	biological_process	entry receptor-mediated virion attachment to host cell
E	0005886	cellular_component	plasma membrane
E	0016020	cellular_component	membrane
E	0019031	cellular_component	viral envelope
E	0019062	biological_process	virion attachment to host cell
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0020002	cellular_component	host cell plasma membrane
E	0033644	cellular_component	host cell membrane
E	0039663	biological_process	membrane fusion involved in viral entry into host cell
E	0042802	molecular_function	identical protein binding
E	0044177	cellular_component	host cell Golgi apparatus
E	0044178	cellular_component	host cell Golgi membrane
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0055036	cellular_component	virion membrane
E	0060141	biological_process	symbiont-mediated induction of syncytium formation
E	0098670	biological_process	entry receptor-mediated virion attachment to host cell
F	0005886	cellular_component	plasma membrane
F	0016020	cellular_component	membrane
F	0019031	cellular_component	viral envelope
F	0019062	biological_process	virion attachment to host cell
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0020002	cellular_component	host cell plasma membrane
F	0033644	cellular_component	host cell membrane
F	0039663	biological_process	membrane fusion involved in viral entry into host cell
F	0042802	molecular_function	identical protein binding
F	0044177	cellular_component	host cell Golgi apparatus
F	0044178	cellular_component	host cell Golgi membrane
F	0044423	cellular_component	virion component
F	0046718	biological_process	symbiont entry into host cell
F	0055036	cellular_component	virion membrane
F	0060141	biological_process	symbiont-mediated induction of syncytium formation
F	0098670	biological_process	entry receptor-mediated virion attachment to host cell

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2988
Details	TOPO_DOM: Extracellular => ECO:0000269\|PubMed:16160180

Chain	Residue	Details
A	GLN26-ASN524
B	GLN26-ASN524
C	GLN26-ASN524
D	GLN26-ASN524
E	GLN26-ASN524
F	GLN26-ASN524

site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269\|PubMed:11493675, ECO:0000269\|PubMed:12127793

Chain	Residue	Details
A	ARG109
B	ARG109
C	ARG109
D	ARG109
E	ARG109
F	ARG109

site_id	SWS_FT_FI3
Number of Residues	6
Details	SITE: Cleavage; by host furin-like protease => ECO:0000269\|PubMed:11369882, ECO:0000269\|PubMed:12127793

Chain	Residue	Details
A	GLN136
B	GLN136
C	GLN136
D	GLN136
E	GLN136
F	GLN136

site_id	SWS_FT_FI4
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269\|PubMed:21586636

Chain	Residue	Details
A	ASN27
B	ASN27
C	ASN27
D	ASN27
E	ASN27
F	ASN27

site_id	SWS_FT_FI5
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269\|PubMed:21586636, ECO:0000269\|PubMed:28469033

Chain	Residue	Details
A	ASN70
B	ASN70
C	ASN70
D	ASN70
E	ASN70
F	ASN70

site_id	SWS_FT_FI6
Number of Residues	18
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255

Chain	Residue	Details
A	ASN116
D	ASN116
D	ASN120
D	ASN126
E	ASN116
E	ASN120
E	ASN126
F	ASN116
F	ASN120
F	ASN126
A	ASN120
A	ASN126
B	ASN116
B	ASN120
B	ASN126
C	ASN116
C	ASN120
C	ASN126

site_id	SWS_FT_FI7
Number of Residues	6
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269\|PubMed:21586636, ECO:0000269\|PubMed:24179220

Chain	Residue	Details
A	ASN500
B	ASN500
C	ASN500
D	ASN500
E	ASN500
F	ASN500

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)