6CVQ
Human Aprataxin (Aptx) H201Q bound to RNA-DNA, AMP and Zn product complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Aprataxin | polymer | 180 | 21020.5 | 2 | UniProt (Q7Z2E3) Pfam (PF11969) Pfam (PF16278) In PDB | Homo sapiens (Human) | Forkhead-associated domain histidine triad-like protein,FHA-HIT |
2 | D, G | DNA/RNA (5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3') | polymer | 10 | 3066.0 | 2 | Homo sapiens | ||
3 | E, H | DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3') | polymer | 10 | 3037.0 | 2 | Homo sapiens | ||
4 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
5 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
7 | A, B | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
8 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | water | water | 18.0 | 759 | Chemie (HOH) |
Sequence modifications
A, B: 165 - 340 (UniProt: Q7Z2E3)
PDB | External Database | Details |
---|---|---|
Gly 161 | - | expression tag |
Ser 162 | - | expression tag |
His 163 | - | expression tag |
Met 164 | - | expression tag |
Gln 201 | His 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 54247.1 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1188.7 | |
All* | Total formula weight | 55435.8 |