6CSX

Single particles Cryo-EM structure of AcrB D407A associated with lipid bilayer at 3.0 Angstrom

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C, A	Multidrug efflux pump subunit AcrB	polymer	1057	114692.3	3	UniProt (P31224) Pfam (PF00873) In PDB	Escherichia coli (strain K12)	AcrAB-TolC multidrug efflux pump subunit AcrB,Acridine resistance protein B
2	B, C, A	PHOSPHATIDYLETHANOLAMINE	non-polymer		734.0	18	Chemie (PTY)
3	B	DODECANE	non-polymer		170.3	1	Chemie (D12)

Sequence modifications

B, C, A: 1 - 1049 (UniProt: P31224)

PDB	External Database	Details
Ala 407	Asp 407	engineered mutation
Leu 1050	-	expression tag
Glu 1051	-	expression tag
His 1052	-	expression tag
His 1053	-	expression tag
His 1054	-	expression tag
His 1055	-	expression tag
His 1056	-	expression tag
His 1057	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	344076.9
Non-Polymers*	Number of molecules	19
	Total formula weight	13383.0
All*	Total formula weight	357459.9

*Water molecules are not included.