6CST
Structure of human DNA polymerase kappa with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA polymerase kappa | polymer | 551 | 63287.1 | 2 | UniProt (Q9UBT6) Pfam (PF00817) Pfam (PF11798) Pfam (PF11799) | Homo sapiens (Human) | DINB protein,DINP |
| 2 | C, E (C, P) | DNA (5'-D(P*AP*TP*AP*CP*AP*TP*AP*CP*C)-3') | polymer | 9 | 2683.8 | 2 | synthetic construct | ||
| 3 | D, F (D, T) | DNA (5'-D(P*TP*AP*CP*TP*GP*GP*TP*AP*TP*GP*TP*AP*T)-3') | polymer | 13 | 3996.6 | 2 | synthetic construct | ||
| 4 | G, GA, H, HA (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | I, IA, J, K, L (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | JA, KA, LA, M, N... (B, A) | IODIDE ION | non-polymer | 126.9 | 6 | Chemie (IOD) | |||
| 7 | MA, P, Q, R, S... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 8 | NA, Y (B, A) | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine | non-polymer | 490.2 | 2 | Chemie (DZ4) | |||
| 9 | Z (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 10 | AA, BA, CA, DA, EA... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 9 | Chemie (CL) | |||
| 11 | FA, SA, TA, UA (A, B, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 12 | AB, VA, WA, XA, YA... (T, A, B, C, D...) | water | water | 18.0 | 483 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 526 (UniProt: Q9UBT6)
| PDB | External Database | Details |
|---|---|---|
| Met -24 | - | initiating methionine |
| Ser -23 | - | expression tag |
| Tyr -22 | - | expression tag |
| Tyr -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 139935.0 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 3616.0 | |
| All* | Total formula weight | 143551.0 |
