6CS1
SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, two S1 CTDs in an upwards conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, C, A) | Spike glycoprotein,Fibritin | polymer | 1215 | 134739.3 | 3 | UniProt (P59594) UniProt (D9IEJ2) Pfam (PF16451) Pfam (PF09408) Pfam (PF01601) UniProt (by SIFTS) (P10104) | Human SARS coronavirus (SARS-CoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, I, J, K... (D, F, I, J, K...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, L, Q, U, V... (E, L, Q, U, V...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 4 | G, H, S (G, H, S) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 5 | N, O, P (N, O, P) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 6 | AA, BA, CA, DA, EA... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence modifications
B, C, A: 14 - 1190 (UniProt: P59594)
B, C, A: 1192 - 1219 (UniProt: D9IEJ2)
| PDB | External Database | Details |
|---|---|---|
| Ala 577 | Ser 577 | conflict |
| Pro 968 | Lys 968 | engineered mutation |
| Pro 969 | Val 969 | engineered mutation |
| Gly 1191 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ser 1192 | Ala 457 | linker |
| Gly 1220 | - | expression tag |
| Arg 1221 | - | expression tag |
| Ser 1222 | - | expression tag |
| Leu 1223 | - | expression tag |
| Glu 1224 | - | expression tag |
| Val 1225 | - | expression tag |
| Leu 1226 | - | expression tag |
| Phe 1227 | - | expression tag |
| Gln 1228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 404217.8 | |
| Branched | Number of molecules | 21 |
| Total formula weight | 12317.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 419189.7 |
