6CQT

Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by (-) Stereoisomer of VX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acetylcholinesterase	polymer	542	59447.1	2	UniProt (P22303) Pfam (PF00135) In PDB	Homo sapiens (Human)	AChE
2	C, D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A, B	2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL	non-polymer		310.4	2	Chemie (7PE)
5	A, B	O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP	non-polymer		124.1	2	Chemie (VX)
6		water	water		18.0	1160	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118894.2
Branched	Number of molecules	2
	Total formula weight	1141.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1311.3
All*	Total formula weight	121346.6

*Water molecules are not included.