6CNH
Human PRPF4B in complex with Rebastinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PRP4 homolog | polymer | 351 | 40883.4 | 1 | UniProt (Q13523) Pfam (PF00069) In PDB | Homo sapiens (Human) | PRPF4B, PRP4 kinase, PRP4 pre-mRNA-processing factor 4 homolog |
| 2 | A | 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide | non-polymer | 553.6 | 1 | Chemie (919) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 657 - 1005 (UniProt: Q13523)
| PDB | External Database | Details |
|---|---|---|
| Ser 655 | - | expression tag |
| Met 656 | - | expression tag |
| Leu 754 | Phe 754 | conflict |
| Phe 851 | Val 851 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40883.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 937.8 | |
| All* | Total formula weight | 41821.2 |
