6CN5
HUMAN RETENOID-RELATED ORPHAN RECEPTOR-GAMMA LIGAND- BINDING DOMAIN IN COMPLEX WITH INDOLE LIGAND CP9b IN INVERSE AGONIST CONFORMATION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Nuclear receptor ROR-gamma | polymer | 262 | 30250.9 | 2 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | A, B | 4-cyano-N-{3-[1-(cyclohexanecarbonyl)piperidin-4-yl]-1-methyl-1H-indol-5-yl}pyridine-2-carboxamide | non-polymer | 469.6 | 2 | Chemie (F7M) | |||
| 3 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A, B: 259 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 257 | - | expression tag |
| Pro 258 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60501.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 939.2 | |
| All* | Total formula weight | 61441.0 |
