6CKR
Crystal Structure of BRD4 with QC4956
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 4 | polymer | 126 | 15012.3 | 2 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | C, D (A, B) | N-{3-[2-methyl-6-(1-methyl-1H-pyrazol-4-yl)-1-oxo-1,2-dihydroisoquinolin-4-yl]phenyl}methanesulfonamide | non-polymer | 408.5 | 2 | Chemie (F5V) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30024.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 816.9 | |
| All* | Total formula weight | 30841.5 |
