6CK2
Insulin analog containing a YB26W mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Insulin A chain | polymer | 21 | 2383.7 | 2 | UniProt (P01308) | Homo sapiens | |
| 2 | B, D (B, D) | Insulin B chain | polymer | 30 | 3442.0 | 2 | UniProt (P01308) Pfam (PF00049) | Homo sapiens | |
| 3 | E, G (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F (C) | PHENOL | non-polymer | 94.1 | 1 | Chemie (IPH) | |||
| 5 | H (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Trp 26 | Tyr 50 | engineered mutation |
| Orn 29 | Lys 53 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 11651.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 260.4 | |
| All* | Total formula weight | 11911.7 |
