6CJU

Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	SthK cyclic nucleotide-gated potassium channel	polymer	456	51118.6	4	UniProt (G0GA88) Pfam (PF00520) Pfam (PF07885) Pfam (PF00027) In PDB	Spirochaeta thermophila
2	A, D, B, C	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)
3	C, A, D, B	(1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate	non-polymer		749.0	32	Chemie (PGW)

Sequence modifications

A, B, C, D: 1 - 420 (UniProt: G0GA88)

PDB	External Database	Details
Met -18	-	initiating methionine
Ala -17	-	expression tag
Lys -16	-	expression tag
Asp -15	-	expression tag
Ile -14	-	expression tag
Gly -13	-	expression tag
Ile -12	-	expression tag
Asn -11	-	expression tag
Ser -10	-	expression tag
Asp -9	-	expression tag
Pro -8	-	expression tag
Asn -7	-	expression tag
Ser -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Val -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
Leu 0	-	expression tag
Leu 421	-	expression tag
Glu 422	-	expression tag
Ser 423	-	expression tag
Ser 424	-	expression tag
Gly 425	-	expression tag
Leu 426	-	expression tag
Val 427	-	expression tag
Pro 428	-	expression tag
Arg 429	-	expression tag
Gly 430	-	expression tag
Ser 431	-	expression tag
Val 432	-	expression tag
Lys 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	204474.3
Non-Polymers*	Number of molecules	36
	Total formula weight	25285.0
All*	Total formula weight	229759.3

*Water molecules are not included.