6CJA

Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 in complex with Alanyl-PLP and Serine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Cystathionine beta-lyase	polymer	391	43058.3	4	UniProt (Q5ZX43) Pfam (PF01053) In PDB	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
2	A, B, C, D	(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine	non-polymer		318.2	4	Chemie (F0G)
3	A, C, D	SERINE	non-polymer		105.1	4	Chemie (SER)
4	A, B, C	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	1687	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 383 (UniProt: Q5ZX43)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	172233.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1969.5
All*	Total formula weight	174202.5

*Water molecules are not included.