6CJA
Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 in complex with Alanyl-PLP and Serine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cystathionine beta-lyase | polymer | 391 | 43058.3 | 4 | UniProt (Q5ZX43) Pfam (PF01053) | Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) | |
| 2 | E, I, K, N (A, B, C, D) | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine | non-polymer | 318.2 | 4 | Chemie (F0G) | |||
| 3 | F, H, L, O (A, C, D) | SERINE | non-polymer | 105.1 | 4 | Chemie (SER) | |||
| 4 | G, J, M (A, B, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 1687 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 383 (UniProt: Q5ZX43)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 172233.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1969.5 | |
| All* | Total formula weight | 174202.5 |
