6CGE
Crystal structure of human 17beta-HSD type 1 in ternary complex with PBRM and NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estradiol 17-beta-dehydrogenase 1 | polymer | 328 | 34989.0 | 2 | UniProt (P14061) Pfam (PF00106) | Homo sapiens (Human) | 17-beta-hydroxysteroid dehydrogenase type 1,17-beta-HSD 1,20 alpha-hydroxysteroid dehydrogenase,20-alpha-HSD,E2DH,Placental 17-beta-hydroxysteroid dehydrogenase,Short chain dehydrogenase/reductase family 28C member 1 |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010) | |||
| 3 | D, F (A, B) | 3-{[(14beta,16alpha,17alpha)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide | non-polymer | 496.5 | 2 | Chemie (F0D) PubChem (53494954) PubChem (75593446) PubChem (76047330) PubChem (88991542) PubChem (138615875) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69978.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2479.8 | |
| All* | Total formula weight | 72457.8 |
