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6CG2

Crystal Structure of KDM4A with Compound 8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Lysine-specific demethylase 4Apolymer35040761.44UniProt (O75164)
Pfam (PF02375)
Pfam (PF02373)
Homo sapiens (Human)JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A
2E, H, K, N
(A, B, C, D)
NICKEL (II) IONnon-polymer58.74Chemie (NI)
3F, I, L, O
(A, B, C, D)
ZINC IONnon-polymer65.44Chemie (ZN)
4G, J, M, P
(A, B, C, D)
2-[5-(3-hydroxyphenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acidnon-polymer281.34Chemie (QC2)
5Q, R, S, T
(A, B, C, D)
waterwater18.0508Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight163045.8
Non-Polymers*Number of molecules12
Total formula weight1621.5
All*Total formula weight164667.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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