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6CFK

Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound to protein Y (YfiA) at 2.7A resolution

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BB
(1A, 2A)
23S Ribosomal RNApolymer2915948035.62GenBank (55771382)Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
2B, CB
(1B, 2B)
5S Ribosomal RNApolymer12139188.42GenBank (55771382)Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
3C, DB
(1D, 2D)
50S ribosomal protein L2polymer27630532.62UniProt (Q72I07)
Pfam (PF00181)
Pfam (PF03947)
UniProt (by SIFTS) (P60405)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
4D, EB
(1E, 2E)
50S ribosomal protein L3polymer20622450.22UniProt (P52860)
Pfam (PF00297)
UniProt (by SIFTS) (Q5SHN8)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
5E, FB
(1F, 2F)
50S ribosomal protein L4polymer21023271.92UniProt (Q5SHN9)
Pfam (PF00573)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)L1e
6F, GB
(1G, 2G)
50S ribosomal protein L5polymer18221061.62UniProt (P41201)
Pfam (PF00281)
Pfam (PF00673)
UniProt (by SIFTS) (Q5SHQ0)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)TL4,TthL5
7G, HB
(1H, 2H)
50S ribosomal protein L6polymer18019568.92UniProt (P24316)
Pfam (PF00347)
UniProt (by SIFTS) (P0DOY8)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
8H, IB
(1I, 2I)
50S ribosomal protein L9polymer14816422.22UniProt (Q5SLQ1)
Pfam (PF01281)
Pfam (PF03948)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
9I, JB
(1N, 2N)
50S ribosomal protein L13polymer14015927.92UniProt (Q72IN1)
Pfam (PF00572)
UniProt (by SIFTS) (P60488)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
10J, KB
(1O, 2O)
50S ribosomal protein L14polymer12213323.62UniProt (Q5SHP8)
Pfam (PF00238)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
11K, LB
(1P, 2P)
50S ribosomal protein L15polymer15016319.12UniProt (P74910)
Pfam (PF00828)
UniProt (by SIFTS) (Q5SHQ7)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
12L, MB
(1Q, 2Q)
50S ribosomal protein L16polymer14115993.92UniProt (P60489)
Pfam (PF00252)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
13M, NB
(1R, 2R)
50S ribosomal protein L17polymer11813750.12UniProt (Q72I33)
Pfam (PF01196)
UniProt (by SIFTS) (Q9Z9H5)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
14N, OB
(1S, 2S)
50S ribosomal protein L18polymer11212639.82UniProt (P80320)
Pfam (PF00861)
UniProt (by SIFTS) (Q5SHQ4)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)TL24
15O, PB
(1T, 2T)
50S ribosomal protein L19polymer14617188.82UniProt (P60490)
Pfam (PF01245)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
16P, QB
(1U, 2U)
50S ribosomal protein L20polymer11813779.32UniProt (Q72L76)
Pfam (PF00453)
UniProt (by SIFTS) (P60491)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
17Q, RB
(1V, 2V)
50S ribosomal protein L21polymer10111069.22UniProt (Q72HR2)
Pfam (PF00829)
UniProt (by SIFTS) (P60492)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
18R, SB
(1W, 2W)
50S ribosomal protein L22polymer11312808.12UniProt (P48286)
Pfam (PF00237)
UniProt (by SIFTS) (Q5SHP3)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
19S, TB
(1X, 2X)
50S ribosomal protein L23polymer9610759.82UniProt (Q9RA57)
Pfam (PF00276)
UniProt (by SIFTS) (Q5SHP0)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)L*23
20T, UB
(1Y, 2Y)
50S ribosomal protein L24polymer11012085.62UniProt (Q56435)
Pfam (PF00467)
Pfam (PF17136)
UniProt (by SIFTS) (Q5SHP9)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
21U, VB
(1Z, 2Z)
50S ribosomal protein L25polymer20623238.62UniProt (Q72IA7)
Pfam (PF01386)
Pfam (PF14693)
UniProt (by SIFTS) (Q5SHZ1)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)General stress protein CTC
22V, WB
(10, 20)
50S ribosomal protein L27polymer859529.12UniProt (P60493)
Pfam (PF01016)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
23W, XB
(11, 21)
50S ribosomal protein L28polymer9811004.22UniProt (P60494)
Pfam (PF00830)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
24X, YB
(12, 22)
50S ribosomal protein L29polymer728670.32UniProt (Q72I12)
Pfam (PF00831)
UniProt (by SIFTS) (Q5SHP6)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
25Y, ZB
(13, 23)
50S ribosomal protein L30polymer606799.12UniProt (P74909)
Pfam (PF00327)
UniProt (by SIFTS) (Q5SHQ6)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
26AC, Z
(14, 24)
50S ribosomal protein L31polymer718300.52UniProt (Q72JR0)
Pfam (PF01197)
UniProt (by SIFTS) (Q5SJE1)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
27AA, BC
(15, 25)
50S ribosomal protein L32polymer606722.12UniProt (P80339)
Pfam (PF01783)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
28BA, CC
(16, 26)
50S ribosomal protein L33polymer546632.92UniProt (Q72GW3)
Pfam (PF00471)
UniProt (by SIFTS) (P35871)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
29CA, DC
(17, 27)
50S ribosomal protein L34polymer496132.42UniProt (P80340)
Pfam (PF00468)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
30DA, EC
(18, 28)
50S ribosomal protein L35polymer657506.22UniProt (P80341)
Pfam (PF01632)
UniProt (by SIFTS) (Q5SKU1)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
31EA, FC
(19, 29)
50S ribosomal protein L36polymer374435.42UniProt (P80256)
Pfam (PF00444)
UniProt (by SIFTS) (Q5SHR2)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Ribosomal protein B
32FA, GC
(1a, 2a)
16S Ribosomal RNApolymer1521493864.62GenBank (155076)Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
33GA, HC
(1b, 2b)
30S ribosomal protein S2polymer25629317.72UniProt (P62662)
Pfam (PF00318)
UniProt (by SIFTS) (P80371)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
34HA, IC
(1c, 2c)
30S ribosomal protein S3polymer23926751.12UniProt (P62663)
Pfam (PF07650)
Pfam (PF00189)
UniProt (by SIFTS) (P80372)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
35IA, JC
(1d, 2d)
30S ribosomal protein S4polymer20924373.42UniProt (P62664)
Pfam (PF00163)
Pfam (PF01479)
UniProt (by SIFTS) (P80373)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
36JA, KC
(1e, 2e)
30S ribosomal protein S5polymer16217583.42UniProt (P27152)
Pfam (PF00333)
Pfam (PF03719)
UniProt (by SIFTS) (Q5SHQ5)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
37KA, LC
(1f, 2f)
30S ribosomal protein S6polymer10111988.82UniProt (P23370)
Pfam (PF01250)
UniProt (by SIFTS) (Q5SLP8)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)TS9
38LA, MC
(1g, 2g)
30S ribosomal protein S7polymer15618051.02UniProt (P62667)
Pfam (PF00177)
UniProt (by SIFTS) (P17291)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
39MA, NC
(1h, 2h)
30S ribosomal protein S8polymer13815868.62UniProt (P24319)
Pfam (PF00410)
UniProt (by SIFTS) (P0DOY9)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
40NA, OC
(1i, 2i)
30S ribosomal protein S9polymer12814410.62UniProt (P80374)
Pfam (PF00380)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
41OA, PC
(1j, 2j)
30S ribosomal protein S10polymer10511955.02UniProt (P80375)
Pfam (PF00338)
UniProt (by SIFTS) (Q5SHN7)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
42PA, QC
(1k, 2k)
30S ribosomal protein S11polymer12913737.92UniProt (P62654)
Pfam (PF00411)
UniProt (by SIFTS) (P80376)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
43QA, RC
(1l, 2l)
30S ribosomal protein S12polymer13214683.52UniProt (P17293)
Pfam (PF00164)
UniProt (by SIFTS) (Q5SHN3)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
44RA, SC
(1m, 2m)
30S ribosomal protein S13polymer12614338.92UniProt (P62655)
Pfam (PF00416)
UniProt (by SIFTS) (P80377)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
45SA, TC
(1n, 2n)
30S ribosomal protein S14 type Zpolymer617158.72UniProt (P24320)
Pfam (PF00253)
UniProt (by SIFTS) (P0DOY6)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
46TA, UC
(1o, 2o)
30S ribosomal protein S15polymer8910578.42UniProt (P80378)
Pfam (PF00312)
UniProt (by SIFTS) (Q5SJ76)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
47UA, VC
(1p, 2p)
30S ribosomal protein S16polymer8810410.02UniProt (P62238)
Pfam (PF00886)
UniProt (by SIFTS) (Q5SJH3)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
48VA, WC
(1q, 2q)
30S ribosomal protein S17polymer10512325.72UniProt (P0DOY7)
Pfam (PF00366)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
49WA, XC
(1r, 2r)
30S ribosomal protein S18polymer8810258.32UniProt (P62659)
Pfam (PF01084)
UniProt (by SIFTS) (Q5SLQ0)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
50XA, YC
(1s, 2s)
30S ribosomal protein S19polymer9310605.52UniProt (P80381)
Pfam (PF00203)
UniProt (by SIFTS) (Q5SHP2)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
51YA, ZC
(1t, 2t)
30S ribosomal protein S20polymer10611736.12UniProt (P80380)
Pfam (PF01649)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
52AD, ZA
(1u, 2u)
30S ribosomal protein Thxpolymer273350.02UniProt (P62612)
Pfam (PF17070)
UniProt (by SIFTS) (Q5SIH3)
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
53AB, BD
(1y, 2y)
Ribosome-associated inhibitor Apolymer11312803.62UniProt (P0AD49)
Pfam (PF02482)
Escherichia coli (strain K12)Protein Y,pY,Ribosome associated factor Y,Spot Y
54AAA, AAB, AAC, ABA, ABB...
(1A, 1a, 2A, 1l, 2D...)
MAGNESIUM IONnon-polymer24.32362Chemie (MG)
55CO, UPB
(1A, 2A)
POTASSIUM IONnon-polymer39.12Chemie (K)
56APA, PHC
(1A, 2A)
N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]-D-histidinamidenon-polymer349.32Chemie (EZP)
57AUA, BPA, EFB, HVA, QHC...
(1T, 1A, 1a, 18, 2A...)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.27Chemie (MPD)
58ATA, QRA
(1F, 1B)
ARGININEnon-polymer175.22Chemie (ARG)
59BGB, DVA, IVA, KKC, KUA...
(1n, 16, 19, 2Y, 1Y...)
ZINC IONnon-polymer65.412Chemie (ZN)
60JFB, QQC
(1d, 2d)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
61ARC, ASC, ATC, AUC, BRC...
(1B, 16, 2N, 2f, 1D...)
waterwater18.06555Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains106
Total formula weight4362596.0
Non-Polymers*Number of molecules2389
Total formula weight60851.1
All*Total formula weight4423447.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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