6CE7

Insulin Receptor ectodomain in complex with one insulin molecule

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Insulin receptor	polymer	929	105926.1	2	UniProt (P06213) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF17870) In PDB	Homo sapiens (Human)	IR
2	N	Insulin A chain	polymer	21	2383.7	1	UniProt (P01308) In PDB	Homo sapiens
3	O	Insulin B chain	polymer	30	3403.9	1	UniProt (P01318) Pfam (PF00049) In PDB	Ovis aries
4	P	Insulin receptor subunit alpha	polymer	30	3671.2	1	UniProt (P06213) In PDB	Homo sapiens (Human)	IR

Sequence modifications

B, A: 1 - 917 (UniProt: P06213)

PDB	External Database	Details
His 144	Tyr 171	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	221311.0
All*	Total formula weight	221311.0

*Water molecules are not included.