6CCH
NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Apolipoprotein A-I | polymer | 200 | 23234.3 | 2 | UniProt (P02647) Pfam (PF01442) | Homo sapiens (Human) | ApoA-I, Apolipoprotein A1 |
| 2 | B (B) | GTPase KRas | polymer | 187 | 21302.3 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras |
| 3 | AA, AB, BA, BB, CA... (A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 64 | Chemie (PCW) | |||
| 4 | AC, BC, CC, DC, EC... (A) | O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine | non-polymer | 788.0 | 16 | Chemie (17F) PubChem (16219821) PubChem (58556791) PubChem (57369815) PubChem (125750) PubChem (3451126) PubChem (5830256) PubChem (6438639) PubChem (124226306) PubChem (145954209) PubChem (15409351) PubChem (99650225) PubChem (122607770) PubChem (124629033) PubChem (9547077) PubChem (9547078) PubChem (9898005) | |||
| 5 | FC (B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 6 | GC (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) |
Sequence modifications
A, C: 201 - 398 (UniProt: P02647)
B: 1 - 185 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly 199 | - | expression tag |
| Pro 200 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 67770.9 | |
| Non-Polymers* | Number of molecules | 82 |
| Total formula weight | 63530.9 | |
| All* | Total formula weight | 131301.9 |
