6CBP
Crystal structure of the single chain variable fragment of the DH270.6 bnAb in complex with the Man9-V3 glycopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | Man9-V3 glycopeptide | polymer | 30 | 3368.7 | 1 | UniProt (Q74448) Pfam (PF00516) | Human immunodeficiency virus 1 | |
| 2 | B (A) | DH270.6 single chain variable fragment | polymer | 256 | 27297.1 | 1 | Homo sapiens (Human) | ||
| 3 | C (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | D (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G01760ZU) | |||
| 5 | E (D) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose | branched | 504.4 | 1 | In PDB GlyTouCan (G57891XD) | |||
| 6 | F (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 7 | G, H (P, A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
P: 293 - 304 (UniProt: Q74448)
P: 320 - 336 (UniProt: Q74448)
P: 320 - 336 (UniProt: Q74448)
| PDB | External Database | Details |
|---|---|---|
| Pro 305 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30665.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2506.2 | |
| All* | Total formula weight | 33172.0 |
