6CBO

X-ray structure of GenB1 from micromonospora echinospora in complex with neamine and PLP (as the external aldimine)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	C-6' aminotransferase	polymer	439	47472.6	4	UniProt (Q70KD9) Pfam (PF00202)	Micromonospora echinospora	Gentamicin (Hexosaminyl-6-) aminotransferase I,GntW,Putative glutamate-1-semialdehyde aminotransferase
2	E, H, K (A, B, C)	3[N-MORPHOLINO]PROPANE SULFONIC ACID	non-polymer		209.3	3	Chemie (MPO)
3	F, I, L, N (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4	G, J, M, O (A, B, C, D)	(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2-amino-2,6-dideoxy-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-alpha-D-glucopyranoside	non-polymer		553.5	4	Chemie (DOW)
5	P, Q (D)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	R, S, T, U (A, B, C, D)	water	water		18.0	1614	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 417 (UniProt: Q70KD9)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Glu -9	-	expression tag
Asn -8	-	expression tag
Leu -7	-	expression tag
Tyr -6	-	expression tag
Phe -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	189890.5
Non-Polymers*	Number of molecules	13
	Total formula weight	3282.2
All*	Total formula weight	193172.7

*Water molecules are not included.