6CAP

Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	16S Ribosomal RNA rRNA	polymer	1522	494168.8	1	GenBank (55771382)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
2	B (B)	30S ribosomal protein S2	polymer	234	26987.3	1	UniProt (P80371) Pfam (PF00318)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
3	C (C)	30S ribosomal protein S3	polymer	206	22862.4	1	UniProt (P80372) Pfam (PF07650) Pfam (PF00189)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
4	D (D)	30S ribosomal protein S4	polymer	208	24242.3	1	UniProt (P80373) Pfam (PF00163) Pfam (PF01479)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
5	E (E)	RIBOSOMAL PROTEIN S5	polymer	150	16331.1	1	UniProt (P62665) Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (Q5SHQ5)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
6	F (F)	30S ribosomal protein S6	polymer	101	11988.8	1	UniProt (Q5SLP8) Pfam (PF01250)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)	TS9
7	G (G)	30S ribosomal protein S7	polymer	155	17919.8	1	UniProt (P17291) Pfam (PF00177)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
8	H (H)	30S ribosomal protein S8	polymer	138	15868.6	1	UniProt (P0DOY9) Pfam (PF00410)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
9	I (I)	30S ribosomal protein S9	polymer	127	14279.4	1	UniProt (P80374) Pfam (PF00380)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
10	J (J)	30S ribosomal protein S10	polymer	98	11299.2	1	UniProt (Q5SHN7) Pfam (PF00338)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
11	K (K)	30S ribosomal protein S11	polymer	116	12319.0	1	UniProt (P80376) Pfam (PF00411)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
12	L (L)	30S ribosomal protein S12	polymer	124	13850.4	1	UniProt (Q5SHN3) Pfam (PF00164)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
13	M (M)	30S ribosomal protein S13	polymer	118	13365.6	1	UniProt (P80377) Pfam (PF00416)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
14	N (N)	30S ribosomal protein S14 type Z	polymer	60	7027.5	1	UniProt (P0DOY6) Pfam (PF00253)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
15	O (O)	30S ribosomal protein S15	polymer	87	10390.2	1	UniProt (Q5SJ76) Pfam (PF00312)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
16	P (P)	30S ribosomal protein S16	polymer	83	9924.5	1	UniProt (Q5SJH3) Pfam (PF00886)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
17	Q (Q)	30S ribosomal protein S17	polymer	99	11721.9	1	UniProt (P0DOY7) Pfam (PF00366)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
18	R (R)	30S ribosomal protein S18	polymer	70	8155.8	1	UniProt (Q5SLQ0) Pfam (PF01084)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
19	S (S)	30S ribosomal protein S19	polymer	80	9203.7	1	UniProt (Q5SHP2) Pfam (PF00203)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
20	T (T)	30S ribosomal protein S20	polymer	99	10921.1	1	UniProt (P80380) Pfam (PF01649)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
21	U (U)	30S ribosomal protein Thx	polymer	24	2960.5	1	UniProt (Q5SIH3) Pfam (PF17070)	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)	S31
22	V (Y)	RNA (5'-R(*UP*UP*UP*UP*UP*U)-3')	polymer	6	1792.0	1		Thermus thermophilus HB8
23	W (W)	RNA (5'-R(*GP*GP*GP*AP*UP*UP*GP*AP*AP*AP*AP*UP*CP*CP*C)-3')	polymer	15	4815.9	1		Thermus thermophilus HB8
24	AA, AB, AC, AD, AE... (A, L, M, B, C...)	MAGNESIUM ION	non-polymer		24.3	252	Chemie (MG) PubChem (888)
25	GH (A)	(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside	non-polymer		447.5	1	Chemie (SIS) PubChem (20849284) PubChem (5224) PubChem (65453) PubChem (23789067) PubChem (16757732) PubChem (51340727) PubChem (52785036) PubChem (3071575) PubChem (5284617) PubChem (68111758) PubChem (155901534) PubChem (5702116) PubChem (36119) PubChem (6604411) PubChem (71752202) PubChem (93472696) PubChem (93472697) PubChem (93472698) PubChem (90657841) PubChem (12942014) PubChem (12942020) PubChem (94865130) PubChem (94865132) PubChem (94865133) PubChem (96367587) PubChem (98047664) PubChem (98047665) PubChem (98047667) PubChem (93472699) PubChem (94865131) PubChem (96367588) PubChem (98047666) PubChem (10095151) PubChem (122197250) PubChem (123134108) PubChem (124708572) PubChem (124708573) PubChem (124708574) PubChem (124708575) PubChem (125463018) PubChem (125463019) PubChem (125463020) PubChem (125463021) PubChem (145797059) PubChem (132062459) PubChem (134694036) PubChem (162995154) PubChem (138969941) PubChem (146158589) PubChem (162995153) PubChem (162995155) PubChem (162995156) PubChem (163285275) PubChem (165339214) PubChem (173721903) PubChem (173871471)
26	IJ, OI (N, D)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
27	AK, BK, SJ, TJ, UJ... (Q, T, A, C, D...)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A: 0 - 1544 (GenBank: 55771382)

PDB	External Database	Details
C 13	U 131313	conflict

Q: 2 - 100 (UniProt: P0DOY7)

PDB	External Database	Details
Gln 96	Glu 96	conflict

Contents of the asymmetric unit

Polymers	Number of chains	23
	Total formula weight	772395.7
Non-Polymers*	Number of molecules	255
	Total formula weight	6703.2
All*	Total formula weight	779098.9

*Water molecules are not included.