6C96
Cryo-EM structure of mouse TPC1 channel in the apo state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Two pore calcium channel protein 1 | polymer | 825 | 95414.8 | 2 | UniProt (Q9EQJ0) Pfam (PF00520) | Mus musculus (Mouse) | Voltage-dependent calcium channel protein TPC1 |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, H (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) |
Sequence modifications
A, B: 1 - 817 (UniProt: Q9EQJ0)
| PDB | External Database | Details |
|---|---|---|
| Val 818 | - | expression tag |
| Glu 819 | - | expression tag |
| Ala 820 | - | expression tag |
| Gly 821 | - | expression tag |
| Leu 822 | - | expression tag |
| Val 823 | - | expression tag |
| Pro 824 | - | expression tag |
| Arg 825 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 190829.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 488.4 | |
| All* | Total formula weight | 192166.7 |
