6C93

Effects of the E310A Mutation of Cytochrome P450 4B1 (CYP4B1) on n-Octane binding and Heme Ruffling

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cytochrome P450 4B1	polymer	497	57789.3	1	UniProt (P15128) Pfam (PF00067) In PDB	Oryctolagus cuniculus (Rabbit)	CYPIVB1,Cytochrome P450 isozyme 5
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	N-OCTANE	non-polymer		114.2	1	Chemie (OCT)
4		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A: 20 - 506 (UniProt: P15128)

PDB	External Database	Details
Met 18	-	initiating methionine
Ala 19	-	expression tag
Ala 310	Glu 310	engineered mutation
Ser 507	-	expression tag
Thr 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57789.3
Non-Polymers*	Number of molecules	2
	Total formula weight	730.7
All*	Total formula weight	58520.1

*Water molecules are not included.