6C5Z
Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | UDP-glucose 6-dehydrogenase | polymer | 494 | 55136.0 | 6 | UniProt (O60701) Pfam (PF03721) Pfam (PF00984) Pfam (PF03720) | Homo sapiens (Human) | UDPGDH |
| 2 | G, J, L, N, P (A, C, D, E, F) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 5 | Chemie (NAI) | |||
| 3 | H, I, K, M, O... (A, B, C, D, E...) | URIDINE-5'-DIPHOSPHATE-GLUCOSE | non-polymer | 566.3 | 6 | Chemie (UPG) | |||
| 4 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 494 (UniProt: O60701)
| PDB | External Database | Details |
|---|---|---|
| Leu 225 | Ala 225 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 330816.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 6725.0 | |
| All* | Total formula weight | 337541.1 |
