6C5N
Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase with hydroxyoxamate inhibitor 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ketol-acid reductoisomerase (NADP(+)) | polymer | 339 | 37755.4 | 2 | UniProt (Q2YUF3) Pfam (PF07991) Pfam (PF01450) In PDB | Staphylococcus aureus (strain bovine RF122 / ET3-1) | KARI,Acetohydroxy-acid isomeroreductase,AHIR,Alpha-keto-beta-hydroxylacyl reductoisomerase,Ketol-acid reductoisomerase type 1,Ketol-acid reductoisomerase type I |
2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A, B | [cyclopentyl(hydroxy)amino](oxo)acetic acid | non-polymer | 173.2 | 2 | Chemie (EN4) | |||
5 | A, B | (cyclopentylamino)(oxo)acetic acid | non-polymer | 157.2 | 2 | Chemie (81B) | |||
6 | B | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
7 | water | water | 18.0 | 836 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 334 (UniProt: Q2YUF3)
PDB | External Database | Details |
---|---|---|
His 335 | - | expression tag |
His 336 | - | expression tag |
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75510.9 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2317.8 | |
All* | Total formula weight | 77828.7 |