6C0U
Crystal structure of cAMP-dependent protein kinase Calpha subunit bound with N46
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 354 | 41090.8 | 1 | UniProt (P17612) Pfam (PF00069) | Homo sapiens (Human) | PKA C-alpha |
| 2 | B (A) | N-[(3R,4R)-4-{[4-(2-fluoro-3-methoxy-6-propoxybenzene-1-carbonyl)benzene-1-carbonyl]amino}pyrrolidin-3-yl]-1H-indazole-5-carboxamide | non-polymer | 559.6 | 1 | Chemie (EE4) | |||
| 3 | C, D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 4 | F (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | G (A) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P17612)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41090.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 889.0 | |
| All* | Total formula weight | 41979.8 |
