6BWW
Crystal structure of an acetate and Cymal-5 bound cytochrome P450 2B4 F429H mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 2B4 | polymer | 472 | 53617.5 | 1 | UniProt (P00178) Pfam (PF00067) | Oryctolagus cuniculus (Rabbit) | CYPIIB4,Cytochrome P450 isozyme 2,Cytochrome P450 LM2,Cytochrome P450 type B0,Cytochrome P450 type B1 |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C, D (A) | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE | non-polymer | 494.6 | 2 | Chemie (CM5) | |||
| 4 | E, F, G, H, I... (A) | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
| 5 | M, N, O, P, Q... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | S (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 30 - 491 (UniProt: P00178)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Lys 23 | - | expression tag |
| Thr 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Lys 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Tyr 226 | His 226 | conflict |
| His 429 | Phe 429 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53617.5 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2630.5 | |
| All* | Total formula weight | 56248.1 |
