6BWV
Crystal Structure of the 4-1BB/4-1BBL Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tumor necrosis factor ligand superfamily member 9 | polymer | 156 | 16438.7 | 2 | UniProt (P41273) Pfam (PF00229) In PDB | Homo sapiens (Human) | 4-1BB ligand,4-1BBL |
| 2 | D, E | Tumor necrosis factor receptor superfamily member 9 | polymer | 141 | 15118.0 | 2 | UniProt (Q07011) Pfam (PF00020) In PDB | Homo sapiens (Human) | 4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA |
| 3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, B: 89 - 242 (UniProt: P41273)
D, E: 24 - 160 (UniProt: Q07011)
| PDB | External Database | Details |
|---|---|---|
| Gly 87 | - | expression tag |
| Ser 88 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 121 | Cys 121 | engineered mutation |
| Asp 138 | Asn 138 | engineered mutation |
| Gln 149 | Asn 149 | engineered mutation |
| Gly 161 | - | expression tag |
| Ser 162 | - | expression tag |
| Leu 163 | - | expression tag |
| Gly 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 63113.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 106.1 | |
| All* | Total formula weight | 63219.6 |
