6BWK
Crystal structure of the human MLKL pseudokinase domain T357E/S358E mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mixed lineage kinase domain-like protein | polymer | 287 | 32806.8 | 1 | UniProt (Q8NB16) Pfam (PF07714) | Homo sapiens (Human) | hMLKL |
| 2 | B, C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | F (A) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 190 - 471 (UniProt: Q8NB16)
| PDB | External Database | Details |
|---|---|---|
| Gly 185 | - | expression tag |
| Ala 186 | - | expression tag |
| Met 187 | - | expression tag |
| Gly 188 | - | expression tag |
| Ser 189 | - | expression tag |
| Glu 357 | Thr 357 | engineered mutation |
| Glu 358 | Ser 358 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32806.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 33175.2 |
