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6BRJ

DDR1 bound to VX-680

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Epithelial discoidin domain-containing receptor 1polymer35139252.81UniProt (Q08345)
Pfam (PF07714)
Homo sapiens (human)Epithelial discoidin domain receptor 1,CD167 antigen-like family member A,Cell adhesion kinase,Discoidin receptor tyrosine kinase,HGK2,Mammary carcinoma kinase 10,MCK-10,Protein-tyrosine kinase 3A,Protein-tyrosine kinase RTK-6,TRK E,Tyrosine kinase DDR,Tyrosine-protein kinase CAK
2B
(A)
CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDEnon-polymer464.61Chemie (VX6)
3C
(A)
waterwater18.0104Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39252.8
Non-Polymers*Number of molecules1
Total formula weight464.6
All*Total formula weight39717.4
*Water molecules are not included.

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PDB entries from 2026-01-28

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