6BQQ
Crystal Structure of the Human CAMKK2B in complex with BI2526
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 291 | 33127.3 | 1 | UniProt (Q96RR4) Pfam (PF00069) | Homo sapiens (Human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 2 | B (A) | 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 521.7 | 1 | Chemie (R78) | |||
| 3 | C, D, E (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | F (A) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A: 161 - 449 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Ser 159 | - | expression tag |
| Met 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33127.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 698.8 | |
| All* | Total formula weight | 33826.0 |
