6BOO

Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus with oxaloacetate and coenzyme-A.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, A, C, D)	2-methylcitrate synthase, mitochondrial	polymer	441	48557.4	4	UniProt (B0YD89) Pfam (PF00285)	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)	Methylcitrate synthase,(2S,3S)-2-methylcitrate synthase,Citrate synthase 2
2	E, F, H, J, K (B, A, C, D)	OXALOACETATE ION	non-polymer		131.1	5	Chemie (OAA)
3	G, I (B, A)	COENZYME A	non-polymer		767.5	2	Chemie (COA)
4	L, M, N, O (B, A, C, D)	water	water		18.0	196	Chemie (HOH)

Sequence modifications

B, A, C, D: 29 - 465 (UniProt: B0YD89)

PDB	External Database	Details
Ser 25	-	expression tag
Gly 26	-	expression tag
Ser 27	-	expression tag
Gly 28	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	194229.7
Non-Polymers*	Number of molecules	7
	Total formula weight	2190.4
All*	Total formula weight	196420.1

*Water molecules are not included.