6BOF
Crystal structure of KRAS A146T-GDP demonstrating open switch 1 conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTPase KRas | polymer | 168 | 19170.6 | 2 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras |
| 2 | C, D (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 169 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Thr 146 | Ala 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38341.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 886.4 | |
| All* | Total formula weight | 39227.6 |
