6BLQ

Crystal Structure of IAg7 in complex with insulin mimotope p8E9E

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	H-2 class II histocompatibility antigen, A-D alpha chain	polymer	185	21151.5	1	UniProt (P04228) Pfam (PF00993) Pfam (PF07654) In PDB	Mus musculus (Mouse)
2	B	H2-Ab1 protein	polymer	221	25362.3	1	UniProt (Q31135) Pfam (PF00969) Pfam (PF07654) In PDB	Mus musculus (Mouse)
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	A, B	ISOPROPYL ALCOHOL	non-polymer		60.1	4	Chemie (IPA)
6	A, B	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
7		water	water		18.0	394	Chemie (HOH)

Sequence modifications

B: 5 - 192 (UniProt: Q31135)

PDB	External Database	Details
His -28	-	SEE REMARK 999
Leu -27	-	SEE REMARK 999
Val -26	-	SEE REMARK 999
Glu -25	-	SEE REMARK 999
Arg -24	-	SEE REMARK 999
Leu -23	-	SEE REMARK 999
Tyr -22	-	SEE REMARK 999
Leu -21	-	SEE REMARK 999
Val -20	-	SEE REMARK 999
Cys -19	-	SEE REMARK 999
Gly -18	-	SEE REMARK 999
Glu -17	-	SEE REMARK 999
Glu -16	-	SEE REMARK 999
Gly -15	-	linker
Ala -14	-	linker
Gly -13	-	linker
Gly -12	-	linker
Gly -11	-	linker
Ser -4	-	linker
Leu -3	-	linker
Val -2	-	linker
Gly -1	-	linker
Gly 0	-	linker
Ser 1	-	linker
Gly 2	-	linker
Gly 3	-	linker
Gly 4	-	linker
Gly 193	-	expression tag
Gly 194	-	expression tag
Leu 195	-	expression tag
Val 196	-	expression tag
Pro 197	-	expression tag
Arg 198	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46513.9
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1117.3
All*	Total formula weight	48055.6

*Water molecules are not included.