6BKU
Crystal Structure of the Human CAMKK2B bound to GSK650394
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 291 | 33127.3 | 1 | UniProt (Q96RR4) Pfam (PF00069) In PDB | Homo sapiens (Human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
2 | A | 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | non-polymer | 382.5 | 1 | Chemie (DXV) | |||
3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
4 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A: 162 - 449 (UniProt: Q96RR4)
PDB | External Database | Details |
---|---|---|
Ser 159 | - | expression tag |
Met 160 | - | expression tag |
Gln 161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33127.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 428.5 | |
All* | Total formula weight | 33555.7 |