6BKU
Crystal Structure of the Human CAMKK2B bound to GSK650394
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 291 | 33127.3 | 1 | UniProt (Q96RR4) Pfam (PF00069) | Homo sapiens (Human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 2 | B (A) | 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid | non-polymer | 382.5 | 1 | Chemie (DXV) | |||
| 3 | C (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | D (A) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A: 162 - 449 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Ser 159 | - | expression tag |
| Met 160 | - | expression tag |
| Gln 161 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33127.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 428.5 | |
| All* | Total formula weight | 33555.7 |
