6BJR
Crystal structure of prothrombin mutant S101C/A470C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Prothrombin | polymer | 582 | 66309.9 | 1 | UniProt (P00734) Pfam (PF00594) Pfam (PF00051) Pfam (PF09396) Pfam (PF00089) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 2 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 1 | In PDB GlyTouCan (G90333CG) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 1 - 579 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Cys 101 | Ser 144 | engineered mutation |
| Met 122 | Thr 165 | conflict |
| Cys 470 | Ala 513 | engineered mutation |
| Tyr 580 | - | expression tag |
| Leu 581 | - | expression tag |
| Glu 582 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66309.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 383.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 367.0 | |
| All* | Total formula weight | 67060.3 |
