6BGS

Caspase-3 Mutant - S150Y

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Caspase-3	polymer	175	19835.4	1	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
2	C	Caspase-3	polymer	103	12048.8	1	UniProt (P42574) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1
3	B	Ac-Asp-Glu-Val-Asp-CMK	polymer	6	534.9	1	BIRD (PRD_000238)	Homo sapiens
4		water	water		18.0	293	Chemie (HOH)

Sequence modifications

A: 1 - 175 (UniProt: P42574)

PDB	External Database	Details
Tyr 150	Ser 150	engineered mutation

C: 176 - 277 (UniProt: P42574)

PDB	External Database	Details
His 278	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	32419.1
All*	Total formula weight	32419.1

*Water molecules are not included.