Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008234 | molecular_function | cysteine-type peptidase activity |
C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 25 |
Details | binding site for Ac-Asp-Glu-Val-Asp-CMK chain B |
Chain | Residue |
A | SER58 |
B | HOH103 |
B | HOH104 |
B | HOH105 |
B | HOH106 |
C | TYR204 |
C | SER205 |
C | TRP206 |
C | ARG207 |
C | ASN208 |
C | SER209 |
A | ARG64 |
C | TRP214 |
C | SER249 |
C | PHE250 |
C | HOH321 |
C | HOH329 |
C | HOH360 |
A | HIS121 |
A | GLY122 |
A | GLN161 |
A | CYS163 |
A | HOH327 |
B | HOH101 |
B | HOH102 |
Functional Information from PROSITE/UniProt
site_id | PS01121 |
Number of Residues | 15 |
Details | CASPASE_HIS Caspase family histidine active site. HskrsSfvCvLLSHG |
Chain | Residue | Details |
A | HIS108-GLY122 | |
site_id | PS01122 |
Number of Residues | 12 |
Details | CASPASE_CYS Caspase family cysteine active site. KPKLFIIQACRG |
Chain | Residue | Details |
A | LYS154-GLY165 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | ARG207 | |
A | CYS163 | |
Chain | Residue | Details |
A | LYS11 | |
Chain | Residue | Details |
A | SER26 | |
Chain | Residue | Details |
A | CYS163 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | |
Details | M-CSA 815 |
Chain | Residue | Details |
A | THR62 | electrostatic stabiliser |
A | SER63 | electrostatic stabiliser |
A | HIS121 | electrostatic stabiliser, proton acceptor, proton donor |
A | GLY122 | electrostatic stabiliser |
A | CYS163 | electrostatic stabiliser |