6BGC

The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound glucose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glucose/galactose-binding lipoprotein	polymer	387	41662.3	2	UniProt (Q08255) Pfam (PF13407) Pfam (PF18610)	Treponema pallidum (strain Nichols)
2	C, F (A, B)	beta-D-glucopyranose	non-polymer		180.2	2	Chemie (BGC)
3	D, G (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	E, H (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	I, J (A, B)	water	water		18.0	213	Chemie (HOH)

Sequence modifications

A, B: 11 - 378 (UniProt: Q08255)

PDB	External Database	Details
Met -8	-	expression tag
Gly -7	-	expression tag
Ser -6	-	expression tag
Asp -5	-	expression tag
Lys -4	-	expression tag
Ile -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
Glu 4	-	expression tag
Asn 5	-	expression tag
Leu 6	-	expression tag
Tyr 7	-	expression tag
Phe 8	-	expression tag
Gln 9	-	expression tag
Gly 10	-	expression tag
Ala 145	Trp 170	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83324.6
Non-Polymers*	Number of molecules	6
	Total formula weight	564.6
All*	Total formula weight	83889.2

*Water molecules are not included.