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6BG2

Crystal structure of cGMP-dependent protein kinase Ialpha (PKG Ialpha) catalytic domain in AMP-PNP bound state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(C, B, A, D)
cGMP-dependent protein kinase 1polymer34739473.84UniProt (Q13976)
Pfam (PF00069)
Homo sapiens (Human)cGK1,cGMP-dependent protein kinase I,cGKI
2E, H, K, N
(C, B, A, D)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.24Chemie (ANP)
3F, G, I, J, L...
(C, B, A, D)
MANGANESE (II) IONnon-polymer54.98Chemie (MN)
4Q, R, S, T
(C, B, A, D)
waterwater18.01455Chemie (HOH)
Sequence modifications
C, B, A, D: 327 - 671 (UniProt: Q13976)
PDBExternal DatabaseDetails
Gly 325-expression tag
Ser 326-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight157895.1
Non-Polymers*Number of molecules12
Total formula weight2464.3
All*Total formula weight160359.4
*Water molecules are not included.

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PDB entries from 2025-07-02

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