6BFN
Crystal structure of human IRAK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-1 receptor-associated kinase 1 | polymer | 342 | 37777.3 | 2 | UniProt (P51617) Pfam (PF00069) | Homo sapiens (Human) | IRAK-1 |
| 2 | C, D (A, B) | N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide | non-polymer | 379.4 | 2 | Chemie (DL1) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A, B: 194 - 530 (UniProt: P51617)
| PDB | External Database | Details |
|---|---|---|
| Gly 189 | - | expression tag |
| Ala 190 | - | expression tag |
| Met 191 | - | expression tag |
| Gly 192 | - | expression tag |
| Ser 193 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75554.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 758.8 | |
| All* | Total formula weight | 76313.4 |
