Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue DL1 A 601 |
| Chain | Residue |
| A | ILE218 |
| A | HOH734 |
| A | ALA237 |
| A | TYR288 |
| A | PHE290 |
| A | LEU291 |
| A | PRO292 |
| A | GLY294 |
| A | LEU347 |
| A | ASP358 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue DL1 B 601 |
| Chain | Residue |
| A | ASN281 |
| B | ILE218 |
| B | ALA237 |
| B | TYR288 |
| B | PHE290 |
| B | LEU291 |
| B | PRO292 |
| B | GLY294 |
| B | LEU347 |
| B | ASP358 |
| B | HOH725 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 22 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGGFGCVYrAvmrntv............YAVK |
| Chain | Residue | Details |
| A | ILE218-LYS239 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LiHgDIKssNVLL |
| Chain | Residue | Details |
| A | LEU336-LEU348 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by IRAK4","evidences":[{"source":"PubMed","id":"14625308","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"14625308","evidenceCode":"ECO:0000269"}]} |
