6BE6
ADAM10 Extracellular Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Disintegrin and metalloproteinase domain-containing protein 10 | polymer | 449 | 49562.4 | 4 | UniProt (O14672) Pfam (PF13574) Pfam (PF00200) Pfam (PF21299) | Homo sapiens (Human) | ADAM 10,CDw156,Kuzbanian protein homolog,Mammalian disintegrin-metalloprotease |
| 2 | E (E) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G29481IZ) | |||
| 3 | F (F) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G84676UY) | |||
| 4 | G (G) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G75436UI) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G00702NP) | |||
| 6 | I, L, P, T (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 7 | J, M, Q, U (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 8 | K, N, O, R, S... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 9 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 214 - 654 (UniProt: O14672)
| PDB | External Database | Details |
|---|---|---|
| Gln 267 | Asn 267 | conflict |
| Gln 439 | Asn 439 | conflict |
| Gln 551 | Asn 551 | conflict |
| Gly 655 | - | expression tag |
| Gly 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
| His 659 | - | expression tag |
| His 660 | - | expression tag |
| His 661 | - | expression tag |
| His 662 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198249.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 4454.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1094.4 | |
| All* | Total formula weight | 203797.9 |
