Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Serine/threonine-protein kinase mTOR | polymer | 2549 | 287399.1 | 2 | UniProt (P42345) Pfam (PF11865) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) In PDB | Homo sapiens (Human) | FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR |
2 | D, E | Target of rapamycin complex subunit LST8 | polymer | 326 | 35910.1 | 2 | UniProt (Q9BVC4) Pfam (PF00400) In PDB | Homo sapiens (Human) | TORC subunit LST8,G protein beta subunit-like,Protein GbetaL,Mammalian lethal with SEC13 protein 8,mLST8 |
3 | W, Y | Regulatory-associated protein of mTOR | polymer | 1343 | 150197.0 | 2 | UniProt (Q8N122) Pfam (PF14538) Pfam (PF02985) Pfam (PF00400) In PDB | Homo sapiens (Human) | Raptor,p150 target of rapamycin (TOR)-scaffold protein |
4 | X, Z | Eukaryotic translation initiation factor 4E-binding protein 1 | polymer | 122 | 12951.3 | 2 | UniProt (Q13541) Pfam (PF05456) In PDB | Homo sapiens (Human) | eIF4E-binding protein 1,Phosphorylated heat- and acid-stable protein regulated by insulin 1,PHAS-I |
5 | A, B | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
6 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) |
Sequence modifications
A, B: 1 - 578 (PDB: 6BCX)
A, B: 579 - 2549 (UniProt: P42345)
W, Y: 2 - 1335 (UniProt: Q8N122)
X, Z: 1 - 118 (UniProt: Q13541)
A, B: 579 - 2549 (UniProt: P42345)
W, Y: 2 - 1335 (UniProt: Q8N122)
PDB | External Database | Details |
---|---|---|
Met -7 | - | initiating methionine |
Asp -6 | - | expression tag |
Tyr -5 | - | expression tag |
Lys -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Asp -1 | - | expression tag |
Asp 0 | - | expression tag |
Lys 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Gly -1 | - | expression tag |
Arg 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 972915.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1111.6 | |
All* | Total formula weight | 974026.7 |